Adults 18–34CDC
3in 5
Living with at least one chronic condition
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- 1,840
- Papers read
- 312
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- 44
- Data points matched
The default trajectory
The cost of neglecting your health.
Three in five adults aged eighteen to thirty-four live with at least one chronic condition.
- Brain fog
- Chronic fatigue
- Persistent inflammation
- Poor sleep
- Low mood
- Joint pain
Your dashboard
A personalized protocol.
Your protocol is a ranked registry you can open. Each entry carries what it is, its benefits and risks, the grade of evidence behind it, and the exact protocol. Every claim is cited.
Evidence grade AR-002
Zone 2 and VO₂ max training
The largest single input to VO₂ max, which is in turn the strongest modifiable predictor of all-cause mortality on this whole protocol.
PrimaryHeart & circulationSecondaryMetabolicSecondaryBrain
What it is
Zone 2 is the highest intensity you can hold while lactate stays roughly flat, around 1.5 to 2.0 mmol/L. Held there, the adaptation is mitochondrial density and capillary supply in slow-twitch fibre — the ceiling that harder intervals then reach for.
It is deliberately boring. The value is in accumulated hours, and it costs almost nothing in recovery, which is why it sits underneath everything else rather than competing with it.
Benefits
- Across 122,007 patients followed for a median of 8.4 years, higher cardiorespiratory fitness tracked with lower all-cause mortality, and the benefit did not plateau at the top of the range. (Mandsager et al., 2018)
- Pooled across 33 cohorts, each 1-MET increment in fitness corresponded to roughly 13% lower all-cause mortality and 15% fewer cardiovascular events. (Kodama et al., 2009)
- Adding one interval session on top of an aerobic base raised VO₂ max substantially more than matched-calorie moderate training alone. (Wisløff et al., 2007)
Risks and limits
- Orthopaedic overuse if weekly volume rises faster than about 10% a week. At this dose there is little else.
- The real cost is time: four sessions is about three and a half hours a week, indefinitely.
- Heat and altitude raise heart rate for the same effort. When you change climate, hold the zone by pace or power for the first ten days.
Recommended protocol
- Dose
- 180–240 minutes per week in zone 2, plus one interval session of 4 × 4 minutes at 90–95% of maximum
- Frequency
- Four zone 2 sessions and one interval session per week
- Timing
- Any time of day. Six hours clear of resistance sessions where the schedule allows
- Method
- Cycling, rowing or incline walking at 60–70% of maximum heart rate. Nasal breathing sustainable, full sentences possible
- Duration
- Indefinite. This is a floor you hold, not a block you finish
- Avoid
- Raising weekly volume more than about 10% a week. Judging the zone by heart rate alone for the first ten days after a change of climate
Sources
- Mandsager K, Harb S, Cremer P, et al. Association of cardiorespiratory fitness with long-term mortality among adults undergoing exercise treadmill testing.JAMA Netw Open 2018;1:e183605.
- Kodama S, Saito K, Tanaka S, et al. Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis.JAMA 2009;301:2024–2035.
- Wisløff U, Støylen A, Loennechen JP, et al. Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients.Circulation 2007;115:3086–3094.
Old method vs new method
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The registry
Purely evidence based.
Our team works from the primary literature. Landmark trials, meta-analyses, the papers that failed to replicate, and the regulatory record. We aim to cut through the hype and see the evidence behind it.
- 312
- Interventions logged in the registry
- 1,840
- Papers read in full behind those entries
Gain Years registry312 entries · 1,840 papers
- A Strong human evidence
- B Human, but limited
- C Animal or mechanism
- D Thin or contradicted
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From people a few months in.
I came in taking eleven things. I now take four, and I can tell you what each one is for and which paper it came from.
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Review
Advised by experts.
The rubric is stricter than most of what I referee.
It says plainly where the human evidence stops. Almost nothing else does.
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Every claim traces to a paper I can pull up and disagree with.
Screening takes about ten minutes
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Before you sign up
Questions we get asked first.
Isn't most of this just exercise and sleep?
Largely, yes, and that's the finding. You're paying for the ranking, the dosing, and the confidence that the other three hundred entries were assessed rather than ignored.
Couldn't I just do this with an AI chatbot?
You'd get a plausible list, different every session. This one is graded against 1,840 papers, logged where you can check it, and re-run every month without you asking.
What exactly will I receive?
A dashboard: your entries with dose, cadence, form, cost and citations, everything rejected for you, and a monthly revision. Downloads as a dated PDF.
Do you sell supplements or take affiliate revenue?
No, on both counts. You buy everything elsewhere or do it for free, and we earn nothing when you do.
Can I cancel?
In one click, from the dashboard. It stops renewing at the end of the year you have paid for, and you keep every protocol you have been sent.
Is this medical advice?
No. Anything clinical is flagged for you to take to a doctor, and the entry says so.